Search Results for: unifying microbial mechanisms

Unifying Microbial Mechanisms

Unifying Microbial Mechanisms PDF

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Author: Michael F. Cole
Publisher: Garland Science
ISBN: 0429557833
Size: 41.57 MB
Format: PDF, ePub, Mobi
Category : Science
Languages : en
Pages : 346
View: 5224

Microbial pathogenesis is the study of the mechanisms by which microbes (bacteria, viruses, protozoa, and multicellular parasites) cause infectious disease and make their hosts (humans) ill. Bacterial infections we thought were easily treatable are again a huge cause for concern with the well-publicized rise of antibiotic resistance. There are very few effective antiviral drugs and we live with the threat of epidemics such as bird flu and the outbreaks of viruses such the recent (and ongoing) Ebola crisis. Parasitic diseases such as malaria continue to pose a heavy burden in the developing world and with climate change could spread into the developed world. There is therefore an urgent need to understand microbial mechanisms, with research programmes and university courses dedicated to the subject


Microbial Endocrinology Interkingdom Signaling In Infectious Disease And Health

Microbial Endocrinology  Interkingdom Signaling in Infectious Disease and Health PDF

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Author: Mark Lyte
Publisher: Springer
ISBN: 3319202154
Size: 52.29 MB
Format: PDF, Mobi
Category : Medical
Languages : en
Pages : 374
View: 5290

This new edition highlights the numerous advances made in the field of microbial endocrinology over the last five years. Prominent among these new topics featured is the emergence of the microbiota-gut-brain axis and the role it plays in brain function. Specific focus is given to the role of microbial endocrinology in the evolutionary symbiosis between man and microbe as it relates to both health and disease. With new chapters on the microbiome and its relation to neurochemicals, this new edition brings this important volume up to date.


Schaechter S Mechanisms Of Microbial Disease

Schaechter s Mechanisms of Microbial Disease PDF

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Author:
Publisher: Lippincott Williams & Wilkins
ISBN: 0781787440
Size: 45.25 MB
Format: PDF, ePub
Category : Medical
Languages : en
Pages : 826
View: 2006

Schaechter's Mechanisms of Microbial Disease provides students with a thorough understanding of microbial agents and the pathophysiology of microbial diseases. The text is universally praised for "telling the story of a pathogen" in an engaging way, facilitating learning and recall by emphasizing unifying principles and paradigms, rather than forcing students to memorize isolated facts by rote. The table of contents is uniquely organized by microbial class and by organ system, making it equally at home in traditional and systems-based curricula. Case studies with problem-solving questions give students insight into clinical applications of microbiology, which is ideal for problem-based learning.


Issues In Life Sciences Molecular Biology 2011 Edition

Issues in Life Sciences  Molecular Biology  2011 Edition PDF

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Author:
Publisher: ScholarlyEditions
ISBN: 1464963487
Size: 55.85 MB
Format: PDF
Category : Science
Languages : en
Pages : 3330
View: 5297

Issues in Life Sciences: Molecular Biology / 2011 Edition is a ScholarlyEditions™ eBook that delivers timely, authoritative, and comprehensive information about Life Sciences—Molecular Biology. The editors have built Issues in Life Sciences: Molecular Biology: 2011 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Life Sciences—Molecular Biology in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Issues in Life Sciences: Molecular Biology: 2011 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.


Schaechter S Mechanisms Of Microbial Disease

Schaechter s Mechanisms of Microbial Disease PDF

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Author: N Cary Engleberg
Publisher: Lippincott Williams & Wilkins
ISBN: 197515150X
Size: 12.40 MB
Format: PDF, Docs
Category : Medical
Languages : en
Pages : 880
View: 6005

Lippincott® Connect Featured Title Purchase of the new print edition of this Lippincott® Connect title includes access to the digital version of the book, plus related materials such as videos and multiple-choice Q&A and self-assessments. Known for generations as the most comprehensive foundational text on medical microbiology, Schaechter's Mechanisms of Microbial Disease delivers a thorough understanding of microbial agents and the pathophysiology of microbial diseases. This trusted text is universally praised for "telling the story of a pathogen" in an engaging way, facilitating learning and recall by emphasizing unifying principles and paradigms. Content is uniquely organized by microbial class and by organ system, making it equally at home in traditional and systems-based curricula. This updated 6th Edition reflects the latest advances in the field, including significant enhancements to the coverage of serious threats to global health, respiratory and childhood viruses, and sexually transmitted diseases. New illustrations and additional learning features further clarify concepts, reinforce understanding, and help users confidently prepare for board exams and beyond.


Bacterial Responses To Ph

Bacterial Responses to pH PDF

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Author: Derek J. Chadwick
Publisher: John Wiley & Sons
ISBN: 0470515643
Size: 55.77 MB
Format: PDF, Mobi
Category : Technology & Engineering
Languages : en
Pages : 292
View: 4131

Microbial responses to acidic and alkaline pH are important in many areas of bacteriology. For example, the mechanisms of resistance to acidic pH are important in the understanding of the passage of human pathogens through the acid of the stomach; and an understanding of microbial degradation of alkaline industrial waste is important for the environment. Bringing together contributions from an international and interdisciplinary group of experts working on the many aspects of bacterial cellular responses to pH, this stimulating volume draws together new and innovative work in this area. It delineates both similarities and differences between mechanisms of tolerance and response, providing readers with an invaluable resource on the subject.


Virulence Mechanisms Of Bacterial Pathogens

Virulence Mechanisms of Bacterial Pathogens PDF

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Author: Indira T. Kudva
Publisher: John Wiley & Sons
ISBN: 1555819281
Size: 24.53 MB
Format: PDF
Category : Medical
Languages : en
Pages : 871
View: 1830

Ground-breaking overview of an enduring topic Despite the use of antibiotics, bacterial diseases continue to be a critical issue in public health, and bacterial pathogenesis remains a tantalizing problem for research microbiologists. This new edition of Virulence Mechanisms of Bacterial Pathogens broadly covers the knowledge base surrounding this topic and presents recently unraveled bacterial virulence strategies and cutting-edge therapies. A team of editors, led by USDA scientist Indira Kudva, compiled perspectives from experts to explain the wide variety of mechanisms through which bacterial pathogens cause disease: the host interface, host cell enslavement, and bacterial communication, secretion, defenses, and persistence. A collection of reviews on targeted therapies rounds out the seven sections of this unique book. The new edition provides insights into some of the most recent advances in the area of bacterial pathogenesis, including how metabolism shapes the host-pathogen interface interactions across species and genera mechanisms of the secretion systems evasion, survival, and persistence mechanisms new therapies targeting various adaptive and virulence mechanisms of bacterial pathogens Written to promote discussion, extrapolation, exploration, and multidimensional thinking, Virulence Mechanisms of Bacterial Pathogens serves as a textbook for graduate courses on bacterial pathogenesis and a resource for specialists in bacterial pathogenicity, such as molecular biologists, physician scientists, infectious disease clinicians, dental scientists, veterinarians, molecular biologists, industry researchers, and technicians.


Cellular Molecular Mechanisms In Epigenetic Evolutionary Biology

Cellular Molecular Mechanisms in Epigenetic Evolutionary Biology PDF

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Author: John Torday
Publisher: Springer Nature
ISBN: 3030381331
Size: 36.49 MB
Format: PDF, Mobi
Category : Science
Languages : en
Pages : 214
View: 2630

There has been no mechanistic explanation for evolutionary change consistent with phylogeny in the 150 years since the publication of ‘Origins’. As a result, progress in the field of evolutionary biology has stagnated, relying on descriptive observations and genetic associations rather testable scientific measures. This book illuminates the need for a larger evolutionary-based platform for biology. Like physics and chemistry, biology needs a central theory in order to frame the questions that arise, the way hypotheses are tested, and how to interpret the data in the context of a continuum.The reduction of biology to its self-referential, self-organized properties provides the opportunity to recognize the continuum from the Singularity/Big Bang to Consciousness based on cell-cell communication for homeostasis.


Microbial Ecology And Infectious Disease

Microbial Ecology and Infectious Disease PDF

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Author: Eugene Rosenberg
Publisher: Amer Society for Microbiology
ISBN:
Size: 79.30 MB
Format: PDF, ePub, Mobi
Category : Medical
Languages : en
Pages : 319
View: 1085

Recent research in microbial ecology has revealed new tools and new concepts which can stimulate medical microbiology. Similarly, some of the best research in microbial ecology has been carried out by medical microbiologists trying to understand how microorganisms survive and live in a particular ecological niche in the human body. This new volume emphasizes how interaction between these two disciplines can stimulate new research approaches and lead to unifying concepts. Experts review important new topics in microbiology, including quorum sensing, horizontal gene transfer in Vibrio cholerae, anthrax toxin, invasion mechanisms, bacterial bleaching of corals, response to starvation, cell–to–cell interactions, natural genetic engineering, and prions. Each chapter offers a general introduction to the topic, a specific introduction to the research, a critical evaluation of the most recent research on the subject, and a special section on unresolved questions and future research. The book also provides an up–to–date and comprehensive bibliography. Microbial Ecology and Infectious Disease contains a selection of some of the best recent research in microbial ecology and the mechanisms of infectious disease. It is valuable reading for teachers, students, and researchers in general microbiology, medical microbiology, and microbial ecology.


Advances In Microbial Physiology

Advances in Microbial Physiology PDF

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Author: Robert K. Poole
Publisher: Academic Press
ISBN: 0323850871
Size: 77.93 MB
Format: PDF, ePub, Mobi
Category : Science
Languages : en
Pages : 400
View: 7637

Advances in Microbial Physiology, Volume 78, the latest release in this ongoing series, continues the long tradition of topical, important, cutting-edge reviews in microbiology. This updated release contains the latest information in the field, with comprehensive chapters covering Microbubble Intensification of Bioprocessing, Bacterial cellulose: biosynthesis, production, and applications, Microbial energy management – a product of three broad tradeoffs, and more. Contains contributions from leading authorities in microbial physiology Informs and updates on all the latest developments in the field of microbial physiology


Environmental Microbiology

Environmental Microbiology PDF

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Author: Eugene L. Madsen
Publisher: John Wiley & Sons
ISBN: 1118439589
Size: 75.79 MB
Format: PDF, ePub
Category : Science
Languages : en
Pages : 592
View: 1403

New and expanded for its second edition, Environmental Microbiology: From Genomes to Biogeochemistry¸ Second Edition, is a timely update to a classic text filled with ideas, connections, and concepts that advance an in-depth understanding of this growing segment of microbiology. Core principles are highlighted with an emphasis on the logic of the science and new methods-driven discoveries. Numerous up-to-date examples and applications boxes provide tangible reinforcement of material covered. Study questions at the end of each chapter require students to utilize analytical and quantitative approaches, to define and defend arguments, and to apply microbiological paradigms to their personal interests. Essay assignments and related readings stimulate student inquiry and serve as focal points for teachers to launch classroom discussions. A companion website with downloadable artwork and answers to study questions is also available. Environmental Microbiology: From Genomes to Biogeochemistry, Second Edition, offers a coherent and comprehensive treatment of this dynamic, emerging field, building bridges between basic biology, evolution, genomics, ecology, biotechnology, climate change, and the environmental sciences.


Antimicrobial Peptides And Innate Immunity

Antimicrobial Peptides and Innate Immunity PDF

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Author: Pieter S. Hiemstra
Publisher: Springer Science & Business Media
ISBN: 3034805411
Size: 75.80 MB
Format: PDF, ePub, Mobi
Category : Medical
Languages : en
Pages : 384
View: 2005

Antimicrobial peptides have been the subject of intense research in the past decades, and are now considered as an essential part of the defense system in bacteria, plants, animals and humans. his book provides an update on these effector molecules of the innate immune system both for researchers who are already actively involved in the area, and for those with a general interest in the topic. The book starts with an overview of the evolution of cysteine-containing antimicrobial peptides (including defensins), and the role of these peptides in host defense in plants and micro-organisms. The realization that antimicrobial peptides also display functions distinct from their direct antimicrobial action is the focus of the next chapters, and puts these peptides center stage in immunity and wound repair. Further chapters discuss the role of antimicrobial peptides in disease, by providing an overview of mechanisms in bacterial resistance to antimicrobial peptides and a discussion of their role in inflammatory bowel disease, cystic fibrosis lung disease and chronic obstructive pulmonary disease. Finally, the book shows how knowledge of the function of antimicrobial peptides and their regulation can be used to design new therapies for inflammatory and infectious disorders. This is a very important area of research because of the increase in resistance of micro-organisms to conventional antibiotics. Therefore the use of synthetic or recombinant peptides, or agents that stimulate the endogenous production of antimicrobial peptides, provides an attractive alternative for conventional antibiotics.


Probing The Structure Function Relationships Of Microbial Systems

Probing the Structure Function Relationships of Microbial Systems PDF

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Author: M. Plomp
Publisher:
ISBN:
Size: 54.37 MB
Format: PDF, Docs
Category :
Languages : en
Pages : 3
View: 7422

The elucidation of microbial surface architecture and function is critical to determining mechanisms of pathogenesis, immune response, physicochemical properties, environmental resistance and development of countermeasures against bioterrorist agents. We have utilized high-resolution in vitro AFM for studies of structure, assembly, function and environmental dynamics of several microbial systems including bacteria and bacterial spores. Lateral resolutions of {approx}2.0 nm were achieved on pathogens, in vitro. We have demonstrated, using various species of Bacillus and Clostridium bacterial spores, that in vitro AFM can address spatially explicit spore coat protein interactions, structural dynamics in response to environmental changes, and the life cycle of pathogens at near-molecular resolution under physiological conditions. We found that strikingly different species-dependent crystalline structures of the spore coat appear to be a consequence of nucleation and crystallization mechanisms that regulate the assembly of the outer spore coat, and we proposed a unifying mechanism for outer spore coat self-assembly. Furthermore, we revealed molecular-scale transformations of the spore coat during the germination process, which include profound, previously unrecognized changes of the spore coat. We will present data on the direct visualization of stress-induced environmental response of metal-resistant Arthrobacter oxydans bacteria to Cr (VI) exposure, resulting in the formation of a supramolecular crystalline hexagonal structure on the cell surface. At higher Cr (VI) concentrations the formation of microbial extracellular polymers, which cover microbial colony was observed. High-resolution visualization of stress-induced structures on bacterial surfaces builds a foundation for real time in vitro molecular scale studies of structural dynamics of metal-resistant bacteria in response to environmental stimuli. In the case of the bacterium Chlamedia trachomatis, we were able to identify surface exposed proteins versus proteins embedded in the outer membrane. These studies establish in vitro AFM as a powerful new tool capable of revealing pathogen architecture, structural dynamics and variability at nanometer-to-micrometer scales.


Bacterial Responses To Ph

Bacterial Responses to pH PDF

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Author: Novartis Foundation
Publisher: Wiley
ISBN: 9780471985990
Size: 10.96 MB
Format: PDF, Mobi
Category : Technology & Engineering
Languages : en
Pages : 264
View: 7303

Microbial responses to acidic and alkaline pH are important in many areas of bacteriology. For example, the mechanisms of resistance to acidic pH are important in the understanding of the passage of human pathogens through the acid of the stomach; and an understanding of microbial degradation of alkaline industrial waste is important for the environment. Bringing together contributions from an international and interdisciplinary group of experts working on the many aspects of bacterial cellular responses to pH, this stimulating volume draws together new and innovative work in this area. It delineates both similarities and differences between mechanisms of tolerance and response, providing readers with an invaluable resource on the subject.


Microbial Stress Adaptation And Food Safety

Microbial Stress Adaptation and Food Safety PDF

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Author: Ahmed E. Yousef
Publisher: CRC Press
ISBN: 1420012827
Size: 64.22 MB
Format: PDF, Kindle
Category : Technology & Engineering
Languages : en
Pages : 384
View: 2325

The first book to address the subject, Microbial Stress Adaptation and Food Safety emphasizes the implications of stress adaptation and its consequences for food safety. It covers the basic science, kinetics, mechanisms, assessment, and control of stress adaptation and its impact on the safety of foods produced by minimal processing or non-thermal technologies. World renowned experts in the field provide detailed accounts of problems associated with stress adaptation and suggest methods for overcoming these problems. The book begins with an introduction to the stress adaptation phenomenon and its implications for the safety of food processed by novel technologies. Then it addresses the responses of pathogens to physical and chemical stresses encountered during food processing, such as heat, pressure, dehydration, radiation, added organic acids, and naturally occurring antimicrobials. The adaptation of food microbiota to stress as a survival strategy is covered next, followed by an examination of the broad spectrum of stresses that may increase a pathogen's tenacity and resistance to processing. Other topics include stress adaptation of beneficial lactic acid bacteria and how resistance or adaptation to stress in the processing environment relates to pathogens' ability to cause disease. Finally, the book presents strategies to overcome stress adaptation in foodborne pathogens. The authors suggest practical control measures and emphasize the need for future research to counteract the stress adaptation phenomenon. Microbial Stress Adaptation and Food Safety proposes practical solutions to microbial stress adaptation and its hazardous effects on food safety and human health.


Development Of Microbial Ecological Theory Stability Plasticity And Evolution Of Microbial Ecosystems

Development of Microbial Ecological Theory  Stability  Plasticity  and Evolution of Microbial Ecosystems PDF

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Author: Shin Haruta
Publisher: Frontiers Media SA
ISBN: 2889451690
Size: 76.78 MB
Format: PDF, Mobi
Category :
Languages : en
Pages :
View: 7564

“How can we develop microbial ecological theory?” The development of microbial ecological theory has a long way to reach its goal. Advances in microbial ecological techniques provide novel insights into microbial ecosystems. Articles in this book are challenging to determine the central and general tenets of the ecological theory that describes the features of microbial ecosystems. Their achievements expand the frontiers of current microbial ecology and propose the next step. Assemblage of these diverse articles hopefully helps to go on this long journey with many avenues for advancement of microbial ecology.


Microbial Interventions In Agriculture And Environment

Microbial Interventions in Agriculture and Environment PDF

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Author: Dhananjaya Pratap Singh
Publisher: Springer Nature
ISBN: 981138391X
Size: 46.46 MB
Format: PDF, ePub, Mobi
Category : Technology & Engineering
Languages : en
Pages : 596
View: 4826

Microbial communities and their functions play a crucial role in the management of ecological, environmental and agricultural health on the Earth. Microorganisms are the key identified players for plant growth promotion, plant immunization, disease suppression, induced resistance and tolerance against stresses as the indicative parameters of improved crop productivity and sustainable soil health. Beneficial belowground microbial interactions with the rhizosphere help plants mitigate drought and salinity stresses and alleviate water stresses under the unfavorable environmental conditions in the native soils. Microorganisms that are inhabitants of such environmental conditions have potential solutions for them. There are potential microbial communities that can degrade xenobiotic compounds, pesticides and toxic industrial chemicals and help remediate even heavy metals, and thus they find enormous applications in environmental remediation. Microbes have developed intrinsic metabolic capabilities with specific metabolic networks while inhabiting under specific conditions for many generations and, so play a crucial role. The book Microbial Interventions in Agriculture and Environment is an effort to compile and present a great volume of authentic, high-quality, socially-viable, practical and implementable research and technological work on microbial implications. The whole content of the volume covers protocols, methodologies, applications, interactions, role and impact of research and development aspects on microbial interventions and technological outcomes in prospects of agricultural and environmental domain including crop production, plan-soil health management, food & nutrition, nutrient recycling, land reclamation, clean water systems and agro-waste management, biodegradation & bioremediation, biomass to bioenergy, sanitation and rural livelihood security. The covered topics and sub-topics of the microbial domain have high implications for the targeted and wide readership of researchers, students, faculty and scientists working on these areas along with the agri-activists, policymakers, environmentalists, advisors etc. in the Government, industries and non-government level for reference and knowledge generation.


Bacterial Biofilms

Bacterial Biofilms PDF

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Author: Tony Romeo
Publisher: Springer Science & Business Media
ISBN: 9783540754183
Size: 21.87 MB
Format: PDF, Kindle
Category : Medical
Languages : en
Pages : 294
View: 7558

Throughout the biological world, bacteria thrive predominantly in surface-attached, matrix-enclosed, multicellular communities or biofilms, as opposed to isolated planktonic cells. This choice of lifestyle is not trivial, as it involves major shifts in the use of genetic information and cellular energy, and has profound consequences for bacterial physiology and survival. Growth within a biofilm can thwart immune function and antibiotic therapy and thereby complicate the treatment of infectious diseases, especially chronic and foreign device-associated infections. Modern studies of many important biofilms have advanced well beyond the descriptive stage, and have begun to provide molecular details of the structural, biochemical, and genetic processes that drive biofilm formation and its dispersion. There is much diversity in the details of biofilm development among various species, but there are also commonalities. In most species, environmental and nutritional conditions greatly influence biofilm development. Similar kinds of adhesive molecules often promote biofilm formation in diverse species. Signaling and regulatory processes that drive biofilm development are often conserved, especially among related bacteria. Knowledge of such processes holds great promise for efforts to control biofilm growth and combat biofilm-associated infections. This volume focuses on the biology of biofilms that affect human disease, although it is by no means comprehensive. It opens with chapters that provide the reader with current perspectives on biofilm development, physiology, environmental, and regulatory effects, the role of quorum sensing, and resistance/phenotypic persistence to antimicrobial agents during biofilm growth.


Industrial Medical And Environmental Applications Of Microorganisms

Industrial  medical and environmental applications of microorganisms PDF

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Author: Antonio Méndez-Vilas
Publisher: Wageningen Academic Publishers
ISBN: 9086867952
Size: 24.28 MB
Format: PDF, ePub, Mobi
Category : Science
Languages : en
Pages : 698
View: 422

'Industrial, medical and environmental applications of microorganisms' offers an excellent opportunity to learn about new insights, methods, techniques and advances in applied microbiology. It is useful not only for those traditionally involved in this research area but for everyone that needs to keep up with this diverse discipline. The articles are written by researchers from around the world and focus on seven themes: - Environmental microbiology -Agriculture, soil and forest microbiology -Food microbiology -Industrial microbiology - Medical microbiology -Biotechnologically relevant enzymes and proteins - Methods and techniques - education This book contains a compilation of papers presented at the V International Conference on Environmental Industrial and Applied Microbiology (BioMicroWorld2013), held in Madrid, Spain, in October 2013.


Biofilms And Veterinary Medicine

Biofilms and Veterinary Medicine PDF

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Author: Steven L. Percival
Publisher: Springer Science & Business Media
ISBN: 9783642212895
Size: 28.20 MB
Format: PDF, Kindle
Category : Science
Languages : en
Pages : 258
View: 5680

Biofilms are implicated in many common medical problems including urinary tract infections, catheter infections, middle-ear infections, dental plaque, gingivitis, and some less common but more lethal processes such as endocarditis and infections in cystic fibrosis. However, the true importance of biofilms in the overall process of disease pathogenesis has only recently been recognized. Bacterial biofilms are one of the fundamental reasons for incipient wound healing failure in that they may impair natural cutaneous wound healing and reduce topical antimicrobial efficiency in infected skin wounds. Their existence explains many of the enigmas of microbial infection and a better grasp of the process may well serve to establish a different approach to infection control and management. Biofilms and their associated complications have been found to be involved in up to 80% of all infections. A large number of studies targeted at the bacterial biofilms have been conducted, and many of them are referred to in this book, which is the first of its kind. These clinical observations emphasize the importance of biofilm formation to both superficial and systemic infections, and the inability of current antimicrobial therapies to ‘cure’ the resulting diseases even when the in vitro tests suggest that they should be fully effective. In veterinary medicine the concept of biofilms and their role in the pathogenesis of disease has lagged seriously behind that in human medicine. This is all the more extraordinary when one considers that much of the research has been carried out using veterinary species in experimental situations. The clinical features of biofilms in human medicine is certainly mimicked in the veterinary species but there is an inherent and highly regrettable indifference to the failure of antimicrobial therapy in many veterinary disease situations, and this is probably at its most retrograde in veterinary wound management. Biofilms and Veterinary Medicine is specifically focused on discussing the concerns of biofilms to health and disease in animals and provides a definitive text for veterinary practitioners, medical and veterinary students, and researchers.